Quantitative Neutralizing Antibody Testing

COVID-19 Neutralization Assay and COVID-19 Titers Post-Vaccine Lab Testing

META Lab Dx now provides access to the most comprehensive testing on the market for the antibody that neutralizes the COVID-19 virus. Our new Post-Vaccine Lab Tests are your lab’s next tool in helping your clients and patients return to work and school safely and confidently. We are the only CLIA lab in the country that has validated these tests and we have made the process easy for you to add these tests to your current menu. We can immediately start accepting your samples while we validate the assays in your lab. This allows you to get started sooner adding a valuable new test to your menu that will improve your clients’ patient care, increase your testing capacity, and deliver increased revenue.

Quantitative Neutralizing Antibody Testing

Starting at $28 per Test

COVID-19 Neut. AB Highlights

  • Only antibodies capable of neutralizing the COVID-19 virus
  • Measures post-vaccination immunity levels
  • Quick validation in your lab
  • Favorable reimbursements or client bill pricing:
    • Client pricing: Quantitative Antibody testing: $28
    • 86408 – Neut. AB SarsCov2 Screen = $42.13

COVID-19 Titers Highlights

  • Used to determine if a booster vaccine is needed
  • Proof of titer for employment or school
  • Proof of vaccination
  • Favorable reimbursements or client bill pricing:
    • Client pricing: COVID-19 Titer testing: $48
    • 86408 – Neut. AB SarsCov2 Titer = $79.61 to $105.33

Competitive and Scientific Advantages

Does Not Require BSL-3

Quick Validation

High-throughput=Faster TATs for Referred Samples

Frequently Asked Questions

What are the basic principles of the test?
  • The test is designed for detection of circulating SARS-CoV-2 neutralizing antibodies of all immunoglobulin (Ig) classes in serum or plasma capable of binding to the receptor-binding domain (RBD) and neutralizing or blocking the interaction between the RBD and the angiotensin-converting enzyme 2 (ACE2) receptor.
  • The test is a solid phase enzyme-linked immunosorbent assay (ELISA) using a chromogenic enzyme substrate as an indicator.
Why is this test important?
  • Detects neutralizing antibodies without the need for live virus or advanced biosafety containment laboratories.
  • Detects neutralizing antibodies of all immunoglobulin classes
What is the difference between this test and other COVID-19 antibody tests?
  • COVID-19 antibody tests evaluate antibodies that bind to various parts of the SARS-CoV-2 virus and are total antibody or immunoglobulin specific, IgM and/or IgG. These antibody tests do not detect neutralizing antibodies.
  • This test detects antibodies that have blocking or neutralizing function, and have the ability to block virus entry.
What is the difference between this test and other neutralizing antibody tests?
  • Conventional neutralization tests require advanced biocontainment laboratories, live viruses and cells, and can take multiple days for results.
  • This test does not require live virus or cells and does not require advanced biocontainment laboratories. This test can be performed using general laboratory equipment and the test procedure is only ~ 80 minutes.


Can this test be used to detect acute infection?
  • No, this serology test is used to detect neutralizing antibodies in a patient plasma or serum. This test is not used to diagnose acute SARS-CoV-2 infection.
What equipment is needed to perform this test?
  • This test requires an ELISA plate reader and 37°C incubator without CO₂ supply
Can this test be used with automated systems?
  • Yes, since this is an ELISA-based test, it can be adapted and performed using automated ELISA systems.